Search Results
Overview
| Uniprot ID | Q5D023 |
|---|---|
| Protein Name | Dynein light intermediate chain |
| Gene Name | Dync1li2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 372 | KQQSLLAKQPATPTR |
| 457 | GGVQSTAKKSGQKTV |
| 462 | TAKKSGQKTVLSNVQ |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes
Protein Sequence
10
MAPVGVEKKL
20
LLGPNGPAVA
30
AAGDLTSEEE
40
EGQSLWSSIL
50
SEVSTRARSK
60
LPSGKNILVF
70
GEDGSGKTTL
80
MTKLQGAEHG
90
KKGRGLEYLY
100
LSVHDEDRDD
110
HTRCNVWILD
120
GDLYHKGLLK
130
FAVSAESLRE
140
TLVIFVADMS
150
RPWTIMESLQ
160
KWASVLREHI
170
DKMKIPPEEM
180
RDLERKFMKD
190
FQDYIEPEEG
200
CQGSPQRRGP
210
LTSGSDEDNV
220
ALPLGDNVLT
230
HNLGIPVLVV
240
CTKCDAVSIL
250
EKEHDYRDEH
260
LDFIQAHLRG
270
FCLQYGAALI
280
YTSVKEEKNL
290
DLLYKYIVHK
300
TYGFHFTIPA
310
LVVEKDAVFI
320
PAGWDNEKKI
330
AILHENFTTV
340
KPEDAYEDFI
350
VKPPVRKLVH
360
DKELAAEDEQ
370
VFLMKQQSLL
380
AKQPATPTRT
390
SESPARGPSG
400
SPRTQGRGGP
410
ASVPSASPGT
420
SVKKPDPNIK
430
NNAASEGVLA
440
SFFNSLLSKK
450
TGSPGSPSAG
460
GVQSTAKKSG
470
QKTVLSNVQE
480
ELDRMTRKPD
490
SMVTNSSTEN
EA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005874 | microtubule |
| Molecular Function | GO:0005524 | ATP binding |
| Biological Process | GO:0007018 | microtubule-based movement |
| Cellular Component | GO:0005868 | cytoplasmic dynein complex |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.