Search Results
Overview
| Uniprot ID | Q5F1R6 |
|---|---|
| Protein Name | DnaJ homolog subfamily C member 21 |
| Gene Name | DNAJC21 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 390 | SKKQKKKKQKPAQNY |
Function
May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S rRNA
Protein Sequence
10
MKCHYEALGV
20
RRDASEEELK
30
KAYRKLALKW
40
HPDKNLDNAA
50
EAAEQFKLIQ
60
AAYDVLSDPQ
70
ERAWYDNHRE
80
ALLKGGFDGE
90
YQDDSLDLLR
100
YFTVTCYSGY
110
GDDEKGFYTV
120
YRNVFEMIAK
130
EELESVLEEE
140
VDDFPTFGDS
150
QSDYDTVVHP
160
FYAYWQSFCT
170
QKNFAWKEEY
180
DTRQASNRWE
190
KRAMEKENKK
200
IRDKARKEKN
210
ELVRQLVAFI
220
RKRDKRVQAH
230
RKLVEEQNAE
240
KARKAEEMRR
250
QQKLKQAKLV
260
EQYREQSWMT
270
MANLEKELQE
280
MEARYEKEFG
290
DGSDENEMEE
300
HELKDEEDGK
310
DSDEAEDAEL
320
YDDLYCPACD
330
KSFKTEKAMK
340
NHEKSKKHRE
350
MVALLKQQLE
360
EEEENFSRPQ
370
IDENPLDDNS
380
EEEMEDAPKQ
390
KLSKKQKKKK
400
QKPAQNYDDN
410
FNVNGPGEGV
420
KVDPEDTNLN
430
QDSAKELEDS
440
PQENVSVTEI
450
IKPCDDPKSE
460
AKSVPKPKGK
470
KTKDMKKPVR
480
VPAEPQTMSV
490
LISCTTCHSE
500
FPSRNKLFDH
510
LKATGHARAP
520
SSSSLNSATS
530
SQSKKEKRKN
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005840 | ribosome |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.