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Overview

Uniprot IDQ5FVI4
Protein NameCell cycle exit and neuronal differentiation protein 1
Gene NameCend1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
12 GKSASSPKPDTKVPQ
16 SSPKPDTKVPQATAE
25 PQATAEAKATPAADG
33 ATPAADGKAPLTKPV
38 DGKAPLTKPVKKDAQ
41 APLTKPVKKDAQAEK
48 KKDAQAEKQEQPAAP
6 **MESRGKSASSPKP
61 APGPATTKKTPAKAD

Function

Involved in neuronal differentiation

Protein Sequence

10 MESRGKSASS 20 PKPDTKVPQA 30 TAEAKATPAA 40 DGKAPLTKPV 50 KKDAQAEKQE 60 QPAAPGPATT 70 KKTPAKADPV 80 LLNNHSNLKP 90 APTVPAAPSS 100 PDTTSEPKGP 110 GDGAEEDESN 120 TGGRGPWPCE 130 NLTPLLVAGG 140 VAVATIALIL GVAFLARKK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016020 membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0031982 vesicle
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0021686 cerebellar granular layer maturation
Biological Process GO:0021702 cerebellar Purkinje cell differentiation
Biological Process GO:0021941 negative regulation of cerebellar granule cell precursor proliferation
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0021933 radial glia guided migration of cerebellar granule cell

Reference

[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.