Search Results
Overview
| Uniprot ID | Q5GH76 |
|---|---|
| Protein Name | XK-related protein 4 |
| Gene Name | XKR4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 365 | RDSRDDKKPISYMAV |
Function
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface (PubMed:25231987, PubMed:33725486, PubMed:37696806). Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (PubMed:25231987, PubMed:37696806)
Protein Sequence
10
MAAKSDGRLK
20
MKKSSDVAFT
30
PLQNSDHSGS
40
VQGLAPGLPS
50
GSGAEDEEAA
60
GGGCCPDGGG
70
CSRCCCCCAG
80
SGGSAGSGGS
90
GGVAGPGGGG
100
AGSAALCLRL
110
GREQRRYSLW
120
DCLWILAAVA
130
VYFADVGTDV
140
WLAVDYYLRG
150
QRWWFGLTLF
160
FVVLGSLSVQ
170
VFSFRWFVHD
180
FSTEDSATAA
190
AASSCPQPGA
200
DCKTVVGGGS
210
AAGEGEARPS
220
TPQRQASNAS
230
KSNIAAANSG
240
SNSSGATRAS
250
GKHRSASCSF
260
CIWLLQSLIH
270
ILQLGQIWRY
280
FHTIYLGIRS
290
RQSGENDRWR
300
FYWKMVYEYA
310
DVSMLHLLAT
320
FLESAPQLVL
330
QLCIIVQTHS
340
LQALQGFTAA
350
ASLVSLAWAL
360
ASYQKALRDS
370
RDDKKPISYM
380
AVIIQFCWHF
390
FTIAARVITF
400
ALFASVFQLY
410
FGIFIVLHWC
420
IMTFWIVHCE
430
TEFCITKWEE
440
IVFDMVVGII
450
YIFSWFNVKE
460
GRTRCRLFIY
470
YFVILLENTA
480
LSALWYLYKA
490
PQIADAFAIP
500
ALCVVFSSFL
510
TGVVFMLMYY
520
AFFHPNGPRF
530
GQSPSCACED
540
PAAAFTLPPD
550
VATSTLRSIS
560
NNRSVVSDRD
570
QKFAERDGCV
580
PVFQVRPTAP
590
STPSSRPPRI
600
EESVIKIDLF
610
RNRYPAWERH
620
VLDRSLRKAI
630
LAFECSPSPP
640
RLQYKDDALI
650
QERLEYETTL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:1902742 | apoptotic process involved in development |
| Biological Process | GO:0043652 | engulfment of apoptotic cell |
| Biological Process | GO:0070782 | phosphatidylserine exposure on apoptotic cell surface |
Reference
PMID: N/A