Search Results
Overview
| Uniprot ID | Q5HZF2 |
|---|---|
| Protein Name | WW domain-binding protein 4 |
| Gene Name | Wbp4 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 288 | EKPKTPKKSTNPYGE |
| 355 | DGVAPVFKKRRIENG |
Function
Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex
Protein Sequence
10
MADYWKSQPK
20
KFCDYCKCWI
30
ADNRPSVEFH
40
ERGKNHKENV
50
ARKISEIKQK
60
SLDKAKEEEK
70
ASKEFAAMEA
80
AALKAYQEDL
90
KRLGLQSDIS
100
EPTISPVTNT
110
VQPTPTANQQ
120
KEKKKKKKKK
130
EASKGRWVEG
140
VTADGHCYYY
150
DLVTGASQWE
160
KPEGFQGNLK
170
KTAAKAIWVE
180
GLSEDGYTYY
190
YNTETGESKW
200
EKPDDFIPHG
210
GDVLSSKDSE
220
KLPDTLEDSK
230
SSDSHSDSDD
240
EQKKAGEASA
250
ETKKLIIKFK
260
EKNKSTEKRI
270
GPEIQKEKTT
280
PKQNPSNTNE
290
EKPKTPKKST
300
NPYGEWQEIK
310
QEAESQEEVD
320
LELPSTENEC
330
LSSSEAGAGE
340
IKVVFKEKTV
350
SSLGVAADGV
360
APVFKKRRIE
370
NGKSRNLRQR
GEDE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0070064 | proline-rich region binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0045292 | mRNA cis splicing, via spliceosome |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0008380 | RNA splicing |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Cellular Component | GO:0071005 | U2-type precatalytic spliceosome |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.