Search Results
Overview
| Uniprot ID | Q5I034 |
|---|---|
| Protein Name | Protein CUSTOS |
| Gene Name | Custos |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 219 | LKKKAKKKADADLAA |
Function
Plays a role in the regulation of Wnt signaling pathway during early development
Protein Sequence
10
MVAPSGAMSD
20
SESSSSDSSD
30
AEELARCREA
40
ATPAWGLEQR
50
PREAERPAAG
60
TADTQAPAPQ
70
PSRRREVNQH
80
DEDGNELQTT
90
PEFRAYVAKK
100
LGALLDSSIA
110
IAEVWKKTQQ
120
ARLQQEAKEQ
130
QEAKEQQAAK
140
EEQAAKKEED
150
GFRLFFTSVP
160
GGHEKEASPR
170
PCRKRQPPSS
180
SEDSDEELQR
190
CREAAVSASD
200
ILQESAIHCP
210
AKVEKEAEKK
220
KLKKKAKKKA
230
DADLAAATGL
240
EQVKEAGSVN
250
GDPVLSGTKK
260
KKKKKAKKAR
270
EASLCPPAEC
AAAEPKN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005730 | nucleolus |
| Biological Process | GO:0030178 | negative regulation of Wnt signaling pathway |
| Biological Process | GO:0060061 | Spemann organizer formation |
| Biological Process | GO:0016055 | Wnt signaling pathway |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.