Search Results
Overview
| Uniprot ID | Q5JTV8 |
|---|---|
| Protein Name | Torsin-1A-interacting protein 1 |
| Gene Name | TOR1AIP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 308 | MQNDSILKSELGNQS |
Function
Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina
Protein Sequence
10
MAGDGRRAEA
20
VREGWGVYVT
30
PRAPIREGRG
40
RLAPQNGGSS
50
DAPAYRTPPS
60
RQGRREVRFS
70
DEPPEVYGDF
80
EPLVAKERSP
90
VGKRTRLEEF
100
RSDSAKEEVR
110
ESAYYLRSRQ
120
RRQPRPQETE
130
EMKTRRTTRL
140
QQQHSEQPPL
150
QPSPVMTRRG
160
LRDSHSSEED
170
EASSQTDLSQ
180
TISKKTVRSI
190
QEAPVSEDLV
200
IRLRRPPLRY
210
PRYEATSVQQ
220
KVNFSEEGET
230
EEDDQDSSHS
240
SVTTVKARSR
250
DSDESGDKTT
260
RSSSQYIESF
270
WQSSQSQNFT
280
AHDKQPSVLS
290
SGYQKTPQEW
300
APQTARIRTR
310
MQNDSILKSE
320
LGNQSPSTSS
330
RQVTGQPQNA
340
SFVKRNRWWL
350
LPLIAALASG
360
SFWFFSTPEV
370
ETTAVQEFQN
380
QMNQLKNKYQ
390
GQDEKLWKRS
400
QTFLEKHLNS
410
SHPRSQPAIL
420
LLTAARDAEE
430
ALRCLSEQIA
440
DAYSSFRSVR
450
AIRIDGTDKA
460
TQDSDTVKLE
470
VDQELSNGFK
480
NGQNAAVVHR
490
FESFPAGSTL
500
IFYKYCDHEN
510
AAFKDVALVL
520
TVLLEEETLG
530
TSLGLKEVEE
540
KVRDFLKVKF
550
TNSNTPNSYN
560
HMDPDKLNGL
570
WSRISHLVLP
580
VQPENALKRG
ICL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005637 | nuclear inner membrane |
| Cellular Component | GO:0031965 | nuclear membrane |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0001671 | ATPase activator activity |
| Molecular Function | GO:0051117 | ATPase binding |
| Molecular Function | GO:0008092 | cytoskeletal protein binding |
| Molecular Function | GO:0005521 | lamin binding |
| Biological Process | GO:0071763 | nuclear membrane organization |
| Biological Process | GO:0032781 | positive regulation of ATP-dependent activity |
| Biological Process | GO:0034504 | protein localization to nucleus |
Reference
PMID: N/A