Search Results
Overview
| Uniprot ID | Q5M7A7 |
|---|---|
| Protein Name | CB1 cannabinoid receptor-interacting protein 1 |
| Gene Name | Cnrip1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | VKFYNYHKRDHCQWG |
Function
Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels
Protein Sequence
10
MGDLPGIVRL
20
SIALRIQPND
30
GPVFFKVDGQ
40
RFGQNRTIKL
50
LTGSSYKVEV
60
KIKPTTLQVE
70
NISIGGVLVP
80
LELKCKEPDG
90
ERVVYTGIYD
100
TEGVAPTKSG
110
ERQPIQITMP
120
FTDIGTFETV
130
WQVKFYNYHK
140
RDHCQWGSPF
150
SVIEYECKPN
160
ETRSLMWVNK
ESFL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0098982 | GABA-ergic synapse |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098793 | presynapse |
| Molecular Function | GO:0031718 | type 1 cannabinoid receptor binding |
| Biological Process | GO:2000272 | negative regulation of signaling receptor activity |
| Biological Process | GO:0010469 | regulation of signaling receptor activity |
| Biological Process | GO:0150036 | regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.