Search Results
Overview
| Uniprot ID | Q5M943 |
|---|---|
| Protein Name | THUMP domain-containing protein 1 |
| Gene Name | Thumpd1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 15 | SPPSVGGKRKGKSQF |
| 19 | VGGKRKGKSQFLPAK |
| 26 | KSQFLPAKRARRCDA |
Function
Functions as a tRNA-binding adapter to mediate NAT10-dependent tRNA acetylation modifying cytidine to N4-acetylcytidine (ac4C)
Protein Sequence
10
MAATAQQSPP
20
SVGGKRKGKS
30
QFLPAKRARR
40
CDAGGPRQLE
50
PGLQGILITC
60
NMNERKCVEE
70
AYSLLNEYGD
80
DMYGPEKFID
90
KDQQPSGSEG
100
EDDDAEAALK
110
KEVGDIKAST
120
EKRLRRFQSV
130
ESGANNVVFI
140
RTLGIEPEKL
150
VHHILQDMYK
160
TKKKKTRVIL
170
RMLPVSGTCK
180
AFLEDMKKYA
190
ETFLEPWFKA
200
PNKGTFQIVY
210
KSRNNSHMNR
220
EEVIKELAGI
230
VGSLNSENKV
240
DLTNPEYTVV
250
VEIIKAVCCL
260
SVVKDYVLFR
270
KYNLQEVVKS
280
AKDSRPPPKL
290
GNGKEAQLEP
300
GSKLSQNDPP
310
KGKNNQQAAP
320
ESSEELGQTV
330
PGSETQAGSE
340
GGAKPEPESQ
350
GSEGPKAKEN
ELS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006400 | tRNA modification |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.