Search Results
Overview
| Uniprot ID | Q5PQQ2 |
|---|---|
| Protein Name | WW domain-binding protein 11 |
| Gene Name | Wbp11 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | TSSTKSGKFMNPTDQ |
| 169 | QPPSILKKTSAYGPP |
| 316 | RFADMPGKSRKKKKN |
| 556 | ASAATIEKKATATIS |
| 590 | LRVRRENKGATAVPQ |
Function
Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity (By similarity)
Protein Sequence
10
MGRRSTSSTK
20
SGKFMNPTDQ
30
ARKEARKREL
40
KKNKKQRMMV
50
RAAVLKMKDP
60
KQIIRDMEKL
70
DEMEFNPVQQ
80
PQLNEKVLKD
90
KRKKLRETFE
100
RILRLYEKEN
110
PDIYKELRKL
120
EVEYEQKRAQ
130
LSQYFDAVKN
140
AQHVEVESIP
150
LPDMPHAPSN
160
ILIQDIPLPG
170
AQPPSILKKT
180
SAYGPPTRAV
190
SILPLLGHGV
200
PRLPPGRKPP
210
GPPPGPPPPQ
220
VLQMYGRKVG
230
FALDLPPRRR
240
DEDMLYSPEL
250
AQRGHDDDMS
260
STSEDDGYPE
270
DMDQDKHDDS
280
TEDSDTDRSD
290
AESDGDEFGH
300
RDDSERDNTE
310
EKKSGLSVRF
320
ADMPGKSRKK
330
KKNMKELTPL
340
QAMMLRMAGQ
350
EIPEEGREVE
360
EFSEEEDDDD
370
SEDSEAEKPS
380
QKQHKEDSHA
390
DGSSAASSQQ
400
QAPPQAVPPS
410
QIQAPPMPGP
420
PPLGPPPAPP
430
LRPPGPPTGL
440
PPGPPPGAPP
450
FLRPPGMPGI
460
RGPLPRLLPP
470
GPPPGRPPGP
480
PPGPPPGLPP
490
GPPPRGPPPR
500
LPPPAPPGIP
510
PPRPGMMRPP
520
LVPPLGPAPP
530
GLFPPAPLPN
540
PGVLSAPPSL
550
IQRPKADDAS
560
AATIEKKATA
570
TISAKPQITN
580
PKAEVTRFVP
590
TALRVRRENK
600
GATAVPQRRS
610
EEDSAVPVAK
620
AAPRSGPSVP
630
VSVQTKDDVY
640
EAFMKEMEGL
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0019888 | protein phosphatase regulator activity |
| Molecular Function | GO:0050699 | WW domain binding |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0008380 | RNA splicing |
| Biological Process | GO:0006364 | rRNA processing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.