Search Results
Overview
| Uniprot ID | Q5PRF9 |
|---|---|
| Protein Name | Protein Smaug homolog 2 |
| Gene Name | SAMD4B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 537 | LLRTFPRKAALEMQN |
Function
Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A
Protein Sequence
10
MMFRDQVGIL
20
AGWFKGWNEC
30
EQTVALLSLL
40
KRVTRTQARF
50
LQLCLEHSLA
60
DCNDIHLLES
70
EANSAAIVSQ
80
WQQESKEKVV
90
SLLLSHLPLL
100
QPGNTEAKSE
110
YMRLLQKVLA
120
YSIESNAFIE
130
ESRQLLSYAL
140
IHPATTLEDR
150
NALALWLSHL
160
EERLASGFRS
170
RPEPSYHSRQ
180
GSDEWGGPAE
190
LGPGEAGPGW
200
QDKPPRENGH
210
VPFHPSSSVP
220
PAINSIGSNA
230
NTGLPCQIHP
240
SPLKRSMSLI
250
PTSPQVPGEW
260
PSPEELGARA
270
AFTTPDHAPL
280
SPQSSVASSG
290
SEQTEEQGSS
300
RNTFQEDGSG
310
MKDVPSWLKS
320
LRLHKYAALF
330
SQMSYEEMMT
340
LTEQHLESQN
350
VTKGARHKIA
360
LSIQKLRERQ
370
SVLKSLEKDV
380
LEGGNLRNAL
390
QELQQIIITP
400
IKAYSVLQAT
410
VAAATTTPTA
420
KDGAPGEPPL
430
PGAEPPLAHP
440
GTDKGTEAKD
450
PPAVENYPPP
460
PAPAPTDGSE
470
PAPAPVADGD
480
IPSQFTRVMG
490
KVCTQLLVSR
500
PDEENITSYL
510
QLIEKCLTHE
520
AFTETQKKRL
530
LSWKQQVLKL
540
LRTFPRKAAL
550
EMQNYRQQKG
560
WAFGSNSLPI
570
AGSVGMGVAR
580
RTQRQFPMPP
590
RALPPGRMGL
600
LSPSGIGGVS
610
PRHALTSPSL
620
GGQGRQNLWF
630
ANPGGSNSMP
640
SQSRSSVQRT
650
HSLPVHSSPQ
660
AILMFPPDCP
670
VPGPDLEINP
680
TLESLCLSMT
690
EHALGDGTDK
TSTI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000932 | P-body |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0030371 | translation repressor activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening |
Reference
[1] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.