Search Results
Overview
| Uniprot ID | Q5RJK5 |
|---|---|
| Protein Name | - |
| Gene Name | Cbx3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 10 | SNKTTLQKMGKKQNG |
| 103 | DSESDDSKSKKKRDA |
| 21 | KQNGKSKKVEEAEPE |
| 5 | ***MASNKTTLQKMG |
| 92 | EKDGTKRKSLSDSES |
Function
No function data available.
Protein Sequence
10
MASNKTTLQK
20
MGKKQNGKSK
30
KVEEAEPEEF
40
VVEKVLDRRV
50
VNGKVEYFLK
60
WKGFTDADNT
70
WEPEENLDCP
80
ELIEAFLNSQ
90
KAGKEKDGTK
100
RKSLSDSESD
110
DSKSKKKRDA
120
ADKPRGFARG
130
LDPERIIGAT
140
DSSGELMFLM
150
KWKDSDEADL
160
VLAKEANMKC
170
PQIVIAFYEE
180
RLTWHSCPED
EAQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000792 | heterochromatin |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0061793 | chromatin lock complex |
| Cellular Component | GO:0010369 | chromocenter |
| Cellular Component | GO:0000775 | chromosome, centromeric region |
| Cellular Component | GO:0000779 | condensed chromosome, centromeric region |
| Cellular Component | GO:0000791 | euchromatin |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005721 | pericentric heterochromatin |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0090575 | RNA polymerase II transcription regulator complex |
| Cellular Component | GO:0035985 | senescence-associated heterochromatin focus |
| Cellular Component | GO:0090734 | site of DNA damage |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0140297 | DNA-binding transcription factor binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0160267 | histone H1K26me1 reader activity |
| Molecular Function | GO:0160268 | histone H1K26me2 reader activity |
| Molecular Function | GO:0062072 | histone H3K9me2/3 reader activity |
| Molecular Function | GO:1990226 | histone methyltransferase binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0000976 | transcription cis-regulatory region binding |
| Molecular Function | GO:0001221 | transcription coregulator binding |
| Biological Process | GO:0071549 | cellular response to dexamethasone stimulus |
| Biological Process | GO:0006974 | DNA damage response |
| Biological Process | GO:0010467 | gene expression |
| Biological Process | GO:0031507 | heterochromatin formation |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[3] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.