Search Results
Overview
| Uniprot ID | Q5RJL0 |
|---|---|
| Protein Name | Ermin |
| Gene Name | Ermn |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 64 | QEESGNSKGNVLPRG |
Function
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity)
Protein Sequence
10
MTDTPVTLSG
20
SECNGDRPPE
30
NGQQPSSQTR
40
KTTDADETQT
50
YYGVEPSLQH
60
LPAKENQEES
70
GNSKGNVLPR
80
GSEDEKILNE
90
NTEENLFVVH
100
QAIQDLSLQE
110
TSAEDTVFQE
120
GHPWKKIPLN
130
SHNLDMSRQK
140
ERIVHQHLEQ
150
REDESAAHQA
160
TEIEWLGFQK
170
SSQVDILHSK
180
CDEEEEVWNE
190
EINEEDVDEC
200
AEDEGEDEVR
210
VIEFKRKYRE
220
GSPLKEESLA
230
REDSPLSSPS
240
SQPGTPDEQL
250
VLGKKGDIAR
260
NSYSRYNTIS
270
YRKIRKGNTK
280
QRIDEFESMM
HL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005938 | cell cortex |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0030175 | filopodium |
| Cellular Component | GO:0033269 | internode region of axon |
| Cellular Component | GO:0043209 | myelin sheath |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0033270 | paranode region of axon |
| Molecular Function | GO:0051015 | actin filament binding |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0001763 | morphogenesis of a branching structure |
| Biological Process | GO:0031344 | regulation of cell projection organization |
| Biological Process | GO:0008360 | regulation of cell shape |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.