Search Results
Overview
| Uniprot ID | Q5RJT2 |
|---|---|
| Protein Name | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 |
| Gene Name | Ftsj3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | VGKSRRDKFYHLAKE |
Function
RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation
Protein Sequence
10
MGKKGKVGKS
20
RRDKFYHLAK
30
ETGYRSRSAF
40
KLIQLNRRFQ
50
FLQKARALLD
60
LCAAPGGWLQ
70
VAAKFMPVSS
80
LIVGVDLVPI
90
KPLPNVVTLQ
100
EDITTERCRQ
110
ALRKELKTWK
120
VDVVLNDGAP
130
NVGASWVHDA
140
YSQAHLTLMA
150
LRLACDFLAR
160
GGCFITKVFR
170
SRDYQPLLWI
180
FQQLFHRVQA
190
TKPQASRHES
200
AEIFVVCQGF
210
LAPDKVDAKF
220
FDPKFAFKEV
230
EVQAKTVTEL
240
VTKKKPKAEG
250
YAEGDLTLYH
260
RTSVTDFLRA
270
ANPVDFLSKA
280
SEISIDDKEL
290
AQHPATTEDI
300
RACCQDIKVL
310
GRKELRSLLN
320
WRTKLRRYVA
330
KKLKEQAKAL
340
DISLSSEEEG
350
DEEESAAETK
360
QASEEEEERE
370
EEEQLNRTLA
380
EMKAQEVAEL
390
KRKKKKLLRE
400
QRKQRERVEL
410
KMDLPGVSIA
420
DEGETGMFSL
430
RTIRGQQLLE
440
EVTQGDMNAA
450
DTFLSDLPRD
460
DIYVSDAEDD
470
DDTSLESDLD
480
PEELAGVRTH
490
SDQKEQKSLQ
500
FAQVDDSKEE
510
EGENPLLVPL
520
EEKAVLQEEQ
530
ASLWFSKDGF
540
SGIDDDADEA
550
LEISQAQLLY
560
KSRQKEQQPT
570
DPPPPPTNLK
580
TEKKSSQCQN
590
EVPKETEAIT
600
DTGGEDRDSS
610
DSDSSSSEDE
620
DDWKVSRGKK
630
RSRGSKADED
640
GFEVVPIEDP
650
VKYRILDPEG
660
LALGAVIASS
670
KKAKRDLIDN
680
SFNRYAFNEE
690
EEELPEWFVQ
700
EEKQHRIRQL
710
PLDKKEVEHY
720
RKRWREINAR
730
PIKKVAEAKA
740
RKKRRMLKKL
750
EQTKKKAEAV
760
VNTVDISERE
770
KVAQLRSLYK
780
KAGLGKEKRQ
790
VTYVVAKKGV
800
GRKVRRPAGV
810
RGHFKVVDSR
820
MKKDQRAQRK
EQKRNHRRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Cellular Component | GO:0030688 | preribosome, small subunit precursor |
| Molecular Function | GO:0062105 | RNA 2'-O-methyltransferase activity |
| Molecular Function | GO:0016435 | rRNA (guanine) methyltransferase activity |
| Molecular Function | GO:0008650 | rRNA (uridine-2'-O-)-methyltransferase activity |
| Biological Process | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0001510 | RNA methylation |
| Biological Process | GO:0031167 | rRNA methylation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.