Overview
| Uniprot ID | Q5SVS4 |
|---|
| Protein Name | Kidney mitochondrial carrier protein 1 |
|---|
| Gene Name | SLC25A30 |
|---|
| Organism | Homo sapiens |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 7 |
*MSALNWKPFVYGGL |
Function
Antiporter that transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate (PubMed:31356773). The sulfate/sulfate exchange is much higher than the phosphate/phosphate and malate/malate exchanges (PubMed:31356773). The transport affinities is higher for sulfate and thiosulfate than for any other substrate (PubMed:31356773). May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also may mediate a very low unidirectional transport of sulfate, phosphate and (S)-malate (PubMed:31356773)
Protein Sequence
10
MSALNWKPFV
20
YGGLASITAE
30
CGTFPIDLTK
40
TRLQIQGQTN
50
DAKFKEIRYR
60
GMLHALVRIG
70
REEGLKALYS
80
GIAPAMLRQA
90
SYGTIKIGTY
100
QSLKRLFIER
110
PEDETLPINV
120
ICGILSGVIS
130
STIANPTDVL
140
KIRMQAQSNT
150
IQGGMIGNFM
160
NIYQQEGTRG
170
LWKGVSLTAQ
180
RAAIVVGVEL
190
PVYDITKKHL
200
ILSGLMGDTV
210
YTHFLSSFTC
220
GLAGALASNP
230
VDVVRTRMMN
240
QRVLRDGRCS
250
GYTGTLDCLL
260
QTWKNEGFFA
270
LYKGFWPNWL
280
RLGPWNIIFF
290
VTYEQLKKLD
L
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0005743 |
mitochondrial inner membrane |
| Cellular Component |
GO:0005739 |
mitochondrion |
| Molecular Function |
GO:0005452 |
solute:inorganic anion antiporter activity |
| Molecular Function |
GO:0022857 |
transmembrane transporter activity |
| Biological Process |
GO:0015698 |
inorganic anion transport |
Reference
PMID: N/A