Search Results

Overview

Uniprot ID	Q5T1V6
Protein Name	Probable ATP-dependent RNA helicase DDX59
Gene Name	DDX59
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
18	RNANDDGKSCVAKII
23	DGKSCVAKIIKPDPE

Function

No function data available.

Protein Sequence

10 MFVPRSLKIK 20 RNANDDGKSC 30 VAKIIKPDPE 40 DLQLDKSRDV 50 PVDAVATEAA 60 TIDRHISESC 70 PFPSPGGQLA 80 EVHSVSPEQG 90 AKDSHPSEEP 100 VKSFSKTQRW 110 AEPGEPICVV 120 CGRYGEYICD 130 KTDEDVCSLE 140 CKAKHLLQVK 150 EKEEKSKLSN 160 PQKADSEPES 170 PLNASYVYKE 180 HPFILNLQED 190 QIENLKQQLG 200 ILVQGQEVTR 210 PIIDFEHCSL 220 PEVLNHNLKK 230 SGYEVPTPIQ 240 MQMIPVGLLG 250 RDILASADTG 260 SGKTAAFLLP 270 VIMRALFESK 280 TPSALILTPT 290 RELAIQIERQ 300 AKELMSGLPR 310 MKTVLLVGGL 320 PLPPQLYRLQ 330 QHVKVIIATP 340 GRLLDIIKQS 350 SVELCGVKIV 360 VVDEADTMLK 370 MGFQQQVLDI 380 LENIPNDCQT 390 ILVSATIPTS 400 IEQLASQLLH 410 NPVRIITGEK 420 NLPCANVRQI 430 ILWVEDPAKK 440 KKLFEILNDK 450 KLFKPPVLVF 460 VDCKLGADLL 470 SEAVQKITGL 480 KSISIHSEKS 490 QIERKNILKG 500 LLEGDYEVVV 510 STGVLGRGLD 520 LISVRLVVNF 530 DMPSSMDEYV 540 HQIGRVGRLG 550 QNGTAITFIN 560 NNSKRLFWDI 570 AKRVKPTGSI 580 LPPQLLNSPY 590 LHDQKRKEQQ 600 KDKQTQNDLV 610 TGANLMDIIR KHDKSNSQK

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005654	nucleoplasm
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0016887	ATP hydrolysis activity
Molecular Function	GO:0003729	mRNA binding
Molecular Function	GO:0003724	RNA helicase activity
Molecular Function	GO:0008270	zinc ion binding

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.