Search Results

Overview

Uniprot IDQ5T2S8
Protein NameOuter dynein arm-docking complex subunit 2
Gene NameODAD2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
145 GSDYNTMKENSIALN
202 SLSPMTVKKDIELLK

Function

Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (PubMed:27486780). Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (PubMed:23849778)

Protein Sequence

10 MGVALRKLTQ 20 WTAAGHGTGI 30 LEITPLNEAI 40 LKEIIVFVES 50 FIYKHPQEAK 60 FVFVEPLEWN 70 TSLAPSAFES 80 GYVVSETTVK 90 SEEVDKNGQP 100 LLFLSVPQIK 110 IRSFGQLSRL 120 LLIAKTGKLK 130 EAQACVEANR 140 DPIVKILGSD 150 YNTMKENSIA 160 LNILGKITRD 170 DDPESEIKMK 180 IAMLLKQLDL 190 HLLNHSLKHI 200 SLEISLSPMT 210 VKKDIELLKR 220 FSGKGNQTVL 230 ESIEYTSDYE 240 FSNGCRAPPW 250 RQIRGEICYV 260 LVKPHDGETL 270 CITCSAGGVF 280 LNGGKTDDEG 290 DVNYERKGSI 300 YKNLVTFLRE 310 KSPKFSENMS 320 KLGISFSEDQ 330 QKEKDQLGKA 340 PKKEEAAALR 350 KDISGSDKRS 360 LEKNQINFWR 370 NQMTKRWEPS 380 LNWKTTVNYK 390 GKGSAKEIQE 400 DKHTGKLEKP 410 RPSVSHGRAQ 420 LLRKSAEKIE 430 ETVSDSSSES 440 EEDEEPPDHR 450 QEASADLPSE 460 YWQIQKLVKY 470 LKGGNQTATV 480 IALCSMRDFS 490 LAQETCQLAI 500 RDVGGLEVLI 510 NLLETDEVKC 520 KIGSLKILKE 530 ISHNPQIRQN 540 IVDLGGLPIM 550 VNILDSPHKS 560 LKCLAAETIA 570 NVAKFKRARR 580 VVRQHGGITK 590 LVALLDCAHD 600 STKPAQSSLY 610 EARDVEVARC 620 GALALWSCSK 630 SHTNKEAIRK 640 AGGIPLLARL 650 LKTSHENMLI 660 PVVGTLQECA 670 SEENYRAAIK 680 AERIIENLVK 690 NLNSENEQLQ 700 EHCAMAIYQC 710 AEDKETRDLV 720 RLHGGLKPLA 730 SLLNNTDNKE 740 RLAAVTGAIW 750 KCSISKENVT 760 KFREYKAIET 770 LVGLLTDQPE 780 EVLVNVVGAL 790 GECCQERENR 800 VIVRKCGGIQ 810 PLVNLLVGIN 820 QALLVNVTKA 830 VGACAVEPES 840 MMIIDRLDGV 850 RLLWSLLKNP 860 HPDVKASAAW 870 ALCPCIKNAK 880 DAGEMVRSFV 890 GGLELIVNLL 900 KSDNKEVLAS 910 VCAAITNIAK 920 DQENLAVITD 930 HGVVPLLSKL 940 ANTNNNKLRH 950 HLAEAISRCC 960 MWGRNRVAFG 970 EHKAVAPLVR 980 YLKSNDTNVH 990 RATAQALYQL 1000 SEDADNCITM 1010 HENGAVKLLL 1020 DMVGSPDQDL 1030 QEAAAGCISN 1040 IRRLALATEK ARYT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005930 axoneme
Cellular Component GO:0097546 ciliary base
Cellular Component GO:0005929 cilium
Biological Process GO:0003341 cilium movement
Biological Process GO:0007368 determination of left/right symmetry
Biological Process GO:0030317 flagellated sperm motility
Biological Process GO:0036158 outer dynein arm assembly
Biological Process GO:0003356 regulation of cilium beat frequency

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.