Search Results

Overview

Uniprot IDQ5T8P6
Protein NameRNA-binding protein 26
Gene NameRBM26
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
219 ERDLVKPKYDLDRTD
478 PREKPPNKSSMRIVV
504 GEPGVPTKKTWFDKP
505 EPGVPTKKTWFDKPN
510 TKKTWFDKPNFNRTN
523 TNSPGFQKKVQFGNE
524 NSPGFQKKVQFGNEN
705 VYNPAALKAAQKTLL
709 AALKAAQKTLLVSTS
732 KKKQEALKLQQDVRK
786 VLTKNITKLKDEVKA

Function

May be involved in the turnover of nuclear polyadenylated (pA+) RNA

Protein Sequence

10 MVSKMIIENF 20 EALKSWLSKT 30 LEPICDADPS 40 ALAKYVLALV 50 KKDKSEKELK 60 ALCIDQLDVF 70 LQKETQIFVE 80 KLFDAVNTKS 90 YLPPPEQPSS 100 GSLKVEFFPH 110 QEKDIKKEEI 120 TKEEEREKKF 130 SRRLNHSPPQ 140 SSSRYRENRS 150 RDERKKDDRS 160 RKRDYDRNPP 170 RRDSYRDRYN 180 RRRGRSRSYS 190 RSRSRSWSKE 200 RLRERDRDRS 210 RTRSRSRTRS 220 RERDLVKPKY 230 DLDRTDPLEN 240 NYTPVSSVPS 250 ISSGHYPVPT 260 LSSTITVIAP 270 THHGNNTTES 280 WSEFHEDQVD 290 HNSYVRPPMP 300 KKRCRDYDEK 310 GFCMRGDMCP 320 FDHGSDPVVV 330 EDVNLPGMLP 340 FPAQPPVVEG 350 PPPPGLPPPP 360 PILTPPPVNL 370 RPPVPPPGPL 380 PPSLPPVTGP 390 PPPLPPLQPS 400 GMDAPPNSAT 410 SSVPTVVTTG 420 IHHQPPPAPP 430 SLFTADTYDT 440 DGYNPEAPSI 450 TNTSRPMYRH 460 RVHAQRPNLI 470 GLTSGDMDLP 480 PREKPPNKSS 490 MRIVVDSESR 500 KRTIGSGEPG 510 VPTKKTWFDK 520 PNFNRTNSPG 530 FQKKVQFGNE 540 NTKLELRKVP 550 PELNNISKLN 560 EHFSRFGTLV 570 NLQVAYNGDP 580 EGALIQFATY 590 EEAKKAISST 600 EAVLNNRFIK 610 VYWHREGSTQ 620 QLQTTSPKVM 630 QPLVQQPILP 640 VVKQSVKERL 650 GPVPSSTIEP 660 AEAQSASSDL 670 PQNVTKLSVK 680 DRLGFVSKPS 690 VSATEKVLST 700 STGLTKTVYN 710 PAALKAAQKT 720 LLVSTSAVDN 730 NEAQKKKQEA 740 LKLQQDVRKR 750 KQEILEKHIE 760 TQKMLISKLE 770 KNKTMKSEDK 780 AEIMKTLEVL 790 TKNITKLKDE 800 VKAASPGRCL 810 PKSIKTKTQM 820 QKELLDTELD 830 LYKKMQAGEE 840 VTELRRKYTE 850 LQLEAAKRGI 860 LSSGRGRGIH 870 SRGRGAVHGR 880 GRGRGRGRGV 890 PGHAVVDHRP 900 RALEISAFTE 910 SDREDLLPHF 920 AQYGEIEDCQ 930 IDDSSLHAVI 940 TFKTRAEAEA 950 AAVHGARFKG 960 QDLKLAWNKP 970 VTNISAVETE 980 EVEPDEEEFQ 990 EESLVDDSLL 1000 QDDDEEEEDN ESRSWRR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006401 RNA catabolic process

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[3] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[4] Bao Q, Wan N, He Z, Cao J, Yuan W et al.. Subcellular Proteomic Mapping of Lysine Lactylation.. J Am Soc Mass Spectrom 35(12):3221-3232. 2024 Dec 4. PMID: 39569522.

[5] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.