Search Results
Overview
| Uniprot ID | Q5T9A4 |
|---|---|
| Protein Name | ATPase family AAA domain-containing protein 3B |
| Gene Name | ATAD3B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 505 | TEGKRRLKLAQFDYG |
| 94 | LEQQSKLKEYEAAVE |
Function
May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. May act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes
Protein Sequence
10
MSWLFGVNKG
20
PKGEGAGPPP
30
PLPPAQPGAE
40
GGGDRGLGDR
50
PAPKDKWSNF
60
DPTGLERAAK
70
AARELEHSRY
80
AKEALNLAQM
90
QEQTLQLEQQ
100
SKLKEYEAAV
110
EQLKSEQIRA
120
QAEERRKTLS
130
EETRQHQARA
140
QYQDKLARQR
150
YEDQLKQQQL
160
LNEENLRKQE
170
ESVQKQEAMR
180
RATVEREMEL
190
RHKNEMLRVE
200
TEARARAKAE
210
RENADIIREQ
220
IRLKASEHRQ
230
TVLESIRTAG
240
TLFGEGFRAF
250
VTDRDKVTAT
260
VAGLTLLAVG
270
VYSAKNATAV
280
TGRFIEARLG
290
KPSLVRETSR
300
ITVLEALRHP
310
IQVSRRLLSR
320
PQDVLEGVVL
330
SPSLEARVRD
340
IAIATRNTKK
350
NRGLYRHILL
360
YGPPGTGKTL
370
FAKKLALHSG
380
MDYAIMTGGD
390
VAPMGREGVT
400
AMHKLFDWAN
410
TSRRGLLLFM
420
DEADAFLRKR
430
ATEEISKDLR
440
ATLNAFLYHM
450
GQHSNKFMLV
460
LASNLPEQFD
470
CAINSRIDVM
480
VHFDLPQQEE
490
RERLVRLHFD
500
NCVLKPATEG
510
KRRLKLAQFD
520
YGRKCSEVAR
530
LTEGMSGREI
540
AQLAVSWQAT
550
AYASKDGVLT
560
EAMMDACVQD
570
AVQQYRQKMR
580
WLKAEGPGRG
590
VEHPLSGVQG
600
ETLTSWSLAT
610
DPSYPCLAGP
620
CTFRICSWMG
630
TGLCPGPLSP
640
RMSCGGGRPF
CPPGHPLL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0101003 | ficolin-1-rich granule membrane |
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0030667 | secretory granule membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Biological Process | GO:0007005 | mitochondrion organization |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.