Search Results
Overview
| Uniprot ID | Q5TKA1 |
|---|---|
| Protein Name | Protein lin-9 homolog |
| Gene Name | LIN9 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 38 | EKYSSLQKTPVWKGR |
| 43 | LQKTPVWKGRNTSSA |
Function
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition
Protein Sequence
10
MAELDQLPDE
20
SSSAKALVSL
30
KEGSLSNTWN
40
EKYSSLQKTP
50
VWKGRNTSSA
60
VEMPFRNSKR
70
SRLFSDEDDR
80
QINTRSPKRN
90
QRVAMVPQKF
100
TATMSTPDKK
110
ASQKIGFRLR
120
NLLKLPKAHK
130
WCIYEWFYSN
140
IDKPLFEGDN
150
DFCVCLKESF
160
PNLKTRKLTR
170
VEWGKIRRLM
180
GKPRRCSSAF
190
FEEERSALKQ
200
KRQKIRLLQQ
210
RKVADVSQFK
220
DLPDEIPLPL
230
VIGTKVTARL
240
RGVHDGLFTG
250
QIDAVDTLNA
260
TYRVTFDRTG
270
LGTHTIPDYE
280
VLSNEPHETM
290
PIAAFGQKQR
300
PSRFFMTPPR
310
LHYTPPLQSP
320
IIDNDPLLGQ
330
SPWRSKISGS
340
DTETLGGFPV
350
EFLIQVTRLS
360
KILMIKKEHI
370
KKLREMNTEA
380
EKLKSYSMPI
390
SIEFQRRYAT
400
IVLELEQLNK
410
DLNKVLHKVQ
420
QYCYELAPDQ
430
GLQPADQPTD
440
MRRRCEEEAQ
450
EIVRHANSST
460
GQPCVENENL
470
TDLISRLTAI
480
LLQIKCLAEG
490
GDLNSFEFKS
500
LTDSLNDIKS
510
TIDASNISCF
520
QNNVEIHVAH
530
IQSGLSQMGN
540
LHAFAANNTN
RD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0017053 | transcription repressor complex |
| Molecular Function | GO:0003677 | DNA binding |
| Biological Process | GO:0071897 | DNA biosynthetic process |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.