Search Results
Overview
| Uniprot ID | Q5U3Z0 |
|---|---|
| Protein Name | Cilia- and flagella-associated protein 298 |
| Gene Name | Cfap298 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 283 | KRHFHGVKDIKWRPR |
Function
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility. Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway. May suppress canonical Wnt signaling activity
Protein Sequence
10
MVVLHVKRGD
20
ESQFLLQAPG
30
STELEELTAQ
40
VTRVYNGRLK
50
VHRLCTEIEE
60
LAEHGVFLPP
70
NMQGLTDEQI
80
EELKLKDEWG
90
EKCVPSGGSV
100
FTKDDIGRRN
110
GHAPNEKMKQ
120
VLKKTVEEAK
130
AMVSKKQVEA
140
GVFVTMEMVK
150
DALDQLRGAV
160
MIVYPMGLPP
170
YDPIRMEFEN
180
KEDLSGTQAA
190
LEVIQESEAQ
200
LWWAAKELRR
210
TKKLSDYVGK
220
NEKTKIIVKI
230
QQRGQGAPAR
240
EPLISSEEHK
250
QLMLFYHRRQ
260
EELKKLEEND
270
DDSCLNSPWA
280
DNTALKRHFH
290
GVKDIKWRPR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Biological Process | GO:0060271 | cilium assembly |
| Biological Process | GO:0003352 | regulation of cilium movement |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.