Search Results

Overview

Uniprot IDQ5VSF9
Protein NameGlutamate receptor
Gene NameGRIN1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
881 AAVNVWRKNLQSTGG

Function

Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system

Protein Sequence

10 MSTMRLLTLA 20 LLFSCSVARA 30 ACDPKIVNIG 40 AVLSTRKHEQ 50 MFREAVNQAN 60 KRHGSWKIQL 70 NATSVTHKPN 80 AIQMALSVCE 90 DLISSQVYAI 100 LVSHPPTPND 110 HFTPTPVSYT 120 AGFYRIPVLG 130 LTTRMSIYSD 140 KSIHLSFLRT 150 VPPYSHQSSV 160 WFEMMRVYSW 170 NHIILLVSDD 180 HEGRAAQKRL 190 ETLLEERESK 200 SKKRNYENLD 210 QLSYDNKRGP 220 KAEKVLQFDP 230 GTKNVTALLM 240 EAKELEARVI 250 ILSASEDDAA 260 TVYRAAAMLN 270 MTGSGYVWLV 280 GEREISGNAL 290 RYAPDGILGL 300 QLINGKNESA 310 HISDAVGVVA 320 QAVHELLEKE 330 NITDPPRGCV 340 GNTNIWKTGP 350 LFKRVLMSSK 360 YADGVTGRVE 370 FNEDGDRKFA 380 NYSIMNLQNR 390 KLVQVGIYNG 400 THVIPNDRKI 410 IWPGGETEKP 420 RGYQMSTRLK 430 IVTIHQEPFV 440 YVKPTLSDGT 450 CKEEFTVNGD 460 PVKKVICTGP 470 NDTSPGSPRH 480 TVPQCCYGFC 490 IDLLIKLART 500 MNFTYEVHLV 510 ADGKFGTQER 520 VNNSNKKEWN 530 GMMGELLSGQ 540 ADMIVAPLTI 550 NNERAQYIEF 560 SKPFKYQGLT 570 ILVKKEIPRS 580 TLDSFMQPFQ 590 STLWLLVGLS 600 VHVVAVMLYL 610 LDRFSPFGRF 620 KVNSEEEEED 630 ALTLSSAMWF 640 SWGVLLNSGI 650 GEGAPRSFSA 660 RILGMVWAGF 670 AMIIVASYTA 680 NLAAFLVLDR 690 PEERITGIND 700 PRLRNPSDKF 710 IYATVKQSSV 720 DIYFRRQVEL 730 STMYRHMEKH 740 NYESAAEAIQ 750 AVRDNKLHAF 760 IWDSAVLEFE 770 ASQKCDLVTT 780 GELFFRSGFG 790 IGMRKDSPWK 800 QNVSLSILKS 810 HENGFMEDLD 820 KTWVRYQECD 830 SRSNAPATLT 840 FENMAGVFML 850 VAGGIVAGIF 860 LIFIEIAYKR 870 HKDARRKQMQ 880 LAFAAVNVWR 890 KNLQSTGGGR 900 GALQNQKDTV 910 LPRRAIEREE 920 GQLQLCSRHR ES

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030425 dendrite
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0017146 NMDA selective glutamate receptor complex
Cellular Component GO:0098839 postsynaptic density membrane
Molecular Function GO:0016594 glycine binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0004972 NMDA glutamate receptor activity
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0042391 regulation of membrane potential

Reference

PMID: N/A