Search Results
Overview
| Uniprot ID | Q5VZ72 |
|---|---|
| Protein Name | Izumo sperm-egg fusion protein 3 |
| Gene Name | IZUMO3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 226 | KLEELMGKIDEKEEK |
Function
Plays an important role in the biogenesis of the acrosome during sperm development
Protein Sequence
10
MGDLWLFLLL
20
PLSAFHGVKG
30
CLECDPKFIE
40
DVGSLLGNLI
50
PSEVPGRTQL
60
LERQIKEMIH
70
LSFKVSHSDK
80
RLRVLAVQQV
90
VKLRTWLKNE
100
FYKLGNETWK
110
GVFIYQGKLL
120
DVCQNLESKL
130
KELLKNFSEI
140
ACSEDCIVVE
150
GPILDCWTCL
160
RMTNRCFKGE
170
YCGDEDPRKA
180
ENREIALFLI
190
LLATAVILGS
200
AVLLFHFCIF
210
HRRKMKAIRR
220
SLKEYVEKKL
230
EELMGKIDEK
EEKDFRLRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0002079 | inner acrosomal membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0001675 | acrosome assembly |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.