Search Results
Overview
| Uniprot ID | Q5XIF3 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial |
| Gene Name | Ndufs4 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 158 | KVPKPKSKSYGANFS |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Protein Sequence
10
MAAVSMSVSL
20
RQALLRQRAV
30
ATAAVSVCRV
40
PSRLLNTSTW
50
KLADGQTRDT
60
QLITVDEKLD
70
VTPLTGVPEE
80
HIKTRKVRIF
90
VPARNNMQSG
100
VNNTKKWKME
110
FDTRERWENP
120
LMGWASTADP
130
LSNMVLTFSA
140
KEDAVAFAEK
150
HGWSYDVEGR
160
KVPKPKSKSY
170
GANFSWNKRT
RVSTK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045271 | respiratory chain complex I |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Biological Process | GO:0030534 | adult behavior |
| Biological Process | GO:0007628 | adult walking behavior |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0071453 | cellular response to oxygen levels |
| Biological Process | GO:0050890 | cognition |
| Biological Process | GO:0042417 | dopamine metabolic process |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0045087 | innate immune response |
| Biological Process | GO:0032981 | mitochondrial respiratory chain complex I assembly |
| Biological Process | GO:0051402 | neuron apoptotic process |
| Biological Process | GO:0048666 | neuron development |
| Biological Process | GO:0036343 | psychomotor behavior |
| Biological Process | GO:0072593 | reactive oxygen species metabolic process |
| Biological Process | GO:0051881 | regulation of mitochondrial membrane potential |
| Biological Process | GO:0001932 | regulation of protein phosphorylation |
| Biological Process | GO:0022904 | respiratory electron transport chain |
| Biological Process | GO:0003016 | respiratory system process |
| Biological Process | GO:0051591 | response to cAMP |
| Biological Process | GO:0014876 | response to injury involved in regulation of muscle adaptation |
| Biological Process | GO:0007605 | sensory perception of sound |
| Biological Process | GO:0007601 | visual perception |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.