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Overview

Uniprot IDQ5XIG4
Protein NameOCIA domain-containing protein 1
Gene NameOciad1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
197 LEDSPKRKSVTYEEL

Function

Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity)

Protein Sequence

10 MNGRADFREP 20 NAQVSRPIPD 30 IGGGYIPTEE 40 EWRLFAECHE 50 ECFWFRSVPL 60 AATSMLITQG 70 LISKGILSSH 80 PKYGSIPKLI 90 FACIVGYFAG 100 KLSYVKTCQE 110 KFKKLENSPL 120 GEALRSGELR 130 RSLPPGHYTQ 140 KPKYDSNVSG 150 QSSFGTSPAA 160 DNIEKETLPR 170 YEPIPFSASM 180 NESTPTGITD 190 HIAQGPDPNL 200 EDSPKRKSVT 210 YEELRNKNRE 220 SYGVTLSHKT 230 DPSVRPMQER 240 GPQKEVKVNK YGDTWDE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005768 endosome
Biological Process GO:2000736 regulation of stem cell differentiation

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.