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Overview

Uniprot IDQ60870
Protein NameReceptor expression-enhancing protein 5
Gene NameReep5
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
168 ETADAISKEVKKATV
25 LLAKLEAKTGVNRSF

Function

Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes

Protein Sequence

10 MRERFDRFLH 20 EKNCMTDLLA 30 KLEAKTGVNR 40 SFIALGVIGL 50 VALYLVFGYG 60 ASLLCNLIGF 70 GYPAYISMKA 80 IESPNKDDDT 90 QWLTYWVVYG 100 VFSIAEFFSD 110 LFLSWLPFYY 120 MLKCGFLLWC 130 MAPSPANGAE 140 MLYRRIIRPI 150 FLRHESQVDS 160 VVKDVKDKAK 170 ETADAISKEV 180 KKATVNLLGD VKKST

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0071782 endoplasmic reticulum tubular network
Cellular Component GO:0014701 junctional sarcoplasmic reticulum membrane
Cellular Component GO:0033017 sarcoplasmic reticulum membrane
Biological Process GO:0090158 endoplasmic reticulum membrane organization

Reference

[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.