Search Results
Overview
| Uniprot ID | Q61029 |
|---|---|
| Protein Name | Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma |
| Gene Name | Tmpo |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 206 | EPLKGRAKTPVTLKQ |
| 212 | AKTPVTLKQRRTEHN |
Function
May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95 (By similarity)
Protein Sequence
10
MPEFLEDPSV
20
LTKDKLKSEL
30
VANNVTLPAG
40
EQRKDVYVQL
50
YLQHLTARNR
60
PPLAAGANSK
70
GPPDFSSDEE
80
REPTPVLGSG
90
ASVGRGRGAV
100
GRKATKKTDK
110
PRLEDKDDLD
120
VTELSNEELL
130
DQLVRYGVNP
140
GPIVGTTRKL
150
YEKKLLKLRE
160
QGTESRSSTP
170
LPTVSSSAEN
180
TRQNGSNDSD
190
RYSDNDEDSK
200
IELKLEKREP
210
LKGRAKTPVT
220
LKQRRTEHNQ
230
SYSQAGVTET
240
EWTSGSSTGG
250
PLQALTREST
260
RGSRRTPRKR
270
VETSQHFRID
280
GAVISESTPI
290
AETIKASSNE
300
SLVANRLTGN
310
FKHASSILPI
320
TEFSDITRRT
330
PKKPLTRAEV
340
GEKTEERRVD
350
RDILKEMFPY
360
EASTPTGISA
370
SCRRPIKGAA
380
GRPLELSDFR
390
MEESFSSKYV
400
PKYAPLADVK
410
SEKTKKRRSV
420
PMWIKMLLFA
430
LVAVFLFLVY
440
QAMETNQGNP
450
FTNFLQDTKI
SN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0005637 | nuclear inner membrane |
| Molecular Function | GO:0003677 | DNA binding |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.