Search Results
Overview
| Uniprot ID | Q62446 |
|---|---|
| Protein Name | Peptidyl-prolyl cis-trans isomerase FKBP3 |
| Gene Name | Fkbp3 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 99 | DDKPKDSKSEETLDE |
Function
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins (By similarity)
Protein Sequence
10
MAAAVPQRAW
20
TVEQLRSEQL
30
PKKDIIKFLQ
40
DHGSDSFLAE
50
HKLLGNIKNV
60
AKTANKDHLV
70
NAYNHLFESK
80
RFKGTETISK
90
VSEQVKNVKL
100
SDDKPKDSKS
110
EETLDEGPPK
120
YTKSILKKGD
130
KTNFPKKGDV
140
VHCWYTGTLP
150
DGTVFDTNIQ
160
TSSKKKKNAK
170
PLSFKVGVGK
180
VIRGWDEALL
190
TMSKGEKARL
200
EIEPEWAYGK
210
KGQPDAKIPP
220
NTKLIFEVEL
VDID
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.