Search Results
Overview
| Uniprot ID | Q62523 |
|---|---|
| Protein Name | Zyxin |
| Gene Name | Zyx |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 256 | QAPTPAPKFAPVAPK |
Function
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity)
Protein Sequence
10
MAAPRPPPAI
20
SVSVSAPAFY
30
APQKKFAPVV
40
APKPKVNPFR
50
PGDSEPPVAA
60
GAQRAQMGRV
70
GEIPPPPPED
80
FPLPPPPLIG
90
EGDDSEGALG
100
GAFPPPPPPM
110
IEEPFPPAPL
120
EEDIFPSPPP
130
PLEEEGGPEA
140
PTQLPPQPRE
150
KVCSIDLEID
160
SLSSLLDDMT
170
KNDPFKARVS
180
SGYVPPPVAT
190
PFVPKPSTKP
200
APGGTAPLPP
210
WKTPSSSQPP
220
PQPQAKPQVQ
230
LHVQPQAKPH
240
VQPQPVSSAN
250
TQPRGPLSQA
260
PTPAPKFAPV
270
APKFTPVVSK
280
FSPGAPSGPG
290
PQPNQKMVPP
300
DAPSSVSTGS
310
PQPPSFTYAQ
320
QKEKPLVQEK
330
QHPQPPPAQN
340
QNQVRSPGGP
350
GPLTLKEVEE
360
LEQLTQQLMQ
370
DMEHPQRQSV
380
AVNESCGKCN
390
QPLARAQPAV
400
RALGQLFHIT
410
CFTCHQCQQQ
420
LQGQQFYSLE
430
GAPYCEGCYT
440
DTLEKCNTCG
450
QPITDRMLRA
460
TGKAYHPQCF
470
TCVVCACPLE
480
GTSFIVDQAN
490
QPHCVPDYHK
500
QYAPRCSVCS
510
EPIMPEPGRD
520
ETVRVVALDK
530
NFHMKCYKCE
540
DCGKPLSIEA
550
DDNGCFPLDG
560
HVLCRKCHSA
RAQT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0045335 | phagocytic vesicle |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0001725 | stress fiber |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0007160 | cell-matrix adhesion |
| Biological Process | GO:0071346 | cellular response to type II interferon |
| Biological Process | GO:0007229 | integrin-mediated signaling pathway |
| Biological Process | GO:0043149 | stress fiber assembly |
| Biological Process | GO:0007179 | transforming growth factor beta receptor signaling pathway |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.