Search Results
Overview
| Uniprot ID | Q62722 |
|---|---|
| Protein Name | NGFI-A-binding protein 1 |
| Gene Name | Nab1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 126 | SAREPHLKVPKCAAT |
| 129 | EPHLKVPKCAATTCV |
Function
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Also represses multiple types of non-EGR1 activation domains (in vitro)
Protein Sequence
10
MATALPRTLG
20
ELQLYRILQK
30
ANLLSYFDAF
40
IQQGGDDVQQ
50
LCEAGEEEFL
60
EIMALVGMAS
70
KPLHVRRLQK
80
ALRDWVTNPG
90
LFNQPLTSLP
100
VSSIPIYKLP
110
EGSPTWLGIS
120
CNSYERSSSA
130
REPHLKVPKC
140
AATTCVQSLG
150
QGKSEVGSLA
160
LQSVSESRLW
170
QGHHTTESEH
180
SLSPADLGSP
190
ASPKESSEAL
200
DAAAALSVAE
210
CVERMAPTLP
220
KSDLNEVKEL
230
LKNNKKLAKM
240
IGHIFEMSDE
250
DPHKEEEIRK
260
YSAIYGRFDS
270
KRKDGKHLTL
280
HELTVNEAAA
290
QLCVKDNALL
300
TRRDELFALA
310
RQVSREVTYK
320
YTYRTTRLKC
330
GERDELSPKR
340
IKMEDGFPDF
350
QESVPTLFQQ
360
ARAKSEELAG
370
LSSQAEKGMA
380
KQMELLCAQA
390
GYERLQQERR
400
LMAGLYRQSS
410
GEQSPDGGLP
420
SDGSDGQGER
430
PLNLRIPSVQ
440
NRQPHHFVVD
450
GELSRLYSNE
460
VKSHSSESLG
470
ILKDYPHSAF
480
TLEKKVIKTE
PEDSR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003712 | transcription coregulator activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0001958 | endochondral ossification |
| Biological Process | GO:0042552 | myelination |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
| Biological Process | GO:0045682 | regulation of epidermis development |
| Biological Process | GO:0014037 | Schwann cell differentiation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.