Search Results
Overview
| Uniprot ID | Q62763 |
|---|---|
| Protein Name | Casein kinase I isoform gamma-3 |
| Gene Name | Csnk1g3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 207 | HIPYREHKSLTGTAR |
Function
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity)
Protein Sequence
10
MDNKKKDKDK
20
SDDRMARPSG
30
RSGHSTRGTG
40
SSSSGVLMVG
50
PNFRVGKKIG
60
CGNFGELRLG
70
KNLYTNEYVA
80
IKLEPMKSRA
90
PQLHLEYRFY
100
KQLGSGDGIP
110
QVYYFGPCGK
120
YNAMVLELLG
130
PSLEDLFDLC
140
DRTFSLKTVL
150
MIAIQLISRM
160
EYVHSKNLIY
170
RDVKPENFLI
180
GRPGNKAQQV
190
IHIIDFGLAK
200
EYIDPETKKH
210
IPYREHKSLT
220
GTARYMSINT
230
HLGKEQSRRD
240
DLEALGHMFM
250
YFLRGSLPWQ
260
GLKADTLKER
270
YQKIGDTKRA
280
TPIEVLCENF
290
PEEMATYLRY
300
VRRLDFFEKP
310
DYDYLRKLFT
320
DLFDRKGYMF
330
DYEYDWIGKQ
340
LPTPVGAVQQ
350
DPALSSNREA
360
HQHRDKIQQS
370
KNQSADHRAA
380
WDSQQANPHH
390
LRAHLAADRH
400
GGSVQVVSST
410
NGELNTDDPT
420
AGRSNAPITA
430
PTEVEVMDET
440
KCCCFFKRRK
RKTIQRHK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0106310 | protein serine kinase activity |
| Molecular Function | GO:0004674 | protein serine/threonine kinase activity |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| Biological Process | GO:0046777 | protein autophosphorylation |
| Biological Process | GO:0006468 | protein phosphorylation |
| Biological Process | GO:0007165 | signal transduction |
| Biological Process | GO:0016055 | Wnt signaling pathway |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.