Search Results
Overview
| Uniprot ID | Q62813 |
|---|---|
| Protein Name | Limbic system-associated membrane protein |
| Gene Name | Lsamp |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 194 | ITREQSGKYECKAAN |
| 198 | QSGKYECKAANEVSS |
| 209 | EVSSADVKQVKVTVN |
Function
Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hippocampal mossy fiber projection
Protein Sequence
10
MVGRVQPDRK
20
QLPLVLLRLL
30
CLLPTGLPVR
40
SVDFNRGTDN
50
ITVRQGDTAI
60
LRCVVEDKNS
70
KVAWLNRSGI
80
IFAGHDKWSL
90
DPRVELEKRH
100
ALEYSLRIQK
110
VDVYDEGSYT
120
CSVQTQHEPK
130
TSQVYLIVQV
140
PPKISNISSD
150
VTVNEGSNVT
160
LVCMANGRPE
170
PVITWRHLTP
180
LGREFEGEEE
190
YLEILGITRE
200
QSGKYECKAA
210
NEVSSADVKQ
220
VKVTVNYPPT
230
ITESKSNEAT
240
TGRQASLKCE
250
ASAVPAPDFE
260
WYRDDTRINS
270
ANGLEIKSTE
280
GQSSLTVTNV
290
TEEHYGNYTC
300
VAANKLGVTN
310
ASLVLFRPGS
320
VRGINGSISL
330
AVPLWLLAAS
LFCLLSKC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0045211 | postsynaptic membrane |
| Cellular Component | GO:0042734 | presynaptic membrane |
| Cellular Component | GO:0098552 | side of membrane |
| Biological Process | GO:0007157 | heterophilic cell-cell adhesion |
| Biological Process | GO:0035641 | locomotory exploration behavior |
| Biological Process | GO:0051963 | regulation of synapse assembly |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.