Search Results
Overview
| Uniprot ID | Q62826 |
|---|---|
| Protein Name | Heterogeneous nuclear ribonucleoprotein M |
| Gene Name | Hnrnpm |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 611 | HAPGVARKACQIFVR |
Function
Pre-mRNA binding protein, binds avidly to poly(G) and poly(U) RNA homopolymers. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines
Protein Sequence
10
MAAGVEAAAE
20
VAATEPKMEE
30
ESGAPCVPSG
40
NGAPVPKGEE
50
RPTQNEKRKE
60
KNIKRGGNRF
70
EPYANPTKRY
80
RAFITNIPFD
90
VKWQSLKDLV
100
KEKVGEVTYV
110
ELLMDAEGKS
120
RGCAVVEFKM
130
EESMKKAAEV
140
LNKHSLSGRP
150
LKVKEDPDGE
160
HARRAMQKAG
170
RLGSTVFVAN
180
LDYKVGWKKL
190
KEVFSMAGVV
200
VRADILEDKD
210
GKSRGIGTVT
220
FEQSIEAVQA
230
ISMFNGQLLF
240
DRPMHVKMDE
250
RALPKGDFFP
260
PERPQQLPHG
270
LGGIGMGLGP
280
GGQPIDANHL
290
NKGIGMGNLG
300
PAGMGMEGIG
310
FGINKIGGME
320
GPFGGGMENM
330
GRFGSGMNMG
340
RINEILSNAL
350
KRGEIIAKQG
360
GSGAGGSVPG
370
IERMGPGIDR
380
ISGAGMERMG
390
AGLGHGMDRV
400
GSEIERMGLV
410
MDRMGSVERM
420
GSGIERMGPL
430
GLDHMASSIE
440
RMGQTMERIG
450
SGVERMGAGM
460
GFGLERMAAP
470
IDRVGQTIER
480
MGSGVERMGP
490
AIERMGLSMD
500
RMVPTGMGAG
510
LERMGPVMDR
520
MATGLERMGA
530
NNLERMGLER
540
MGANSLERMG
550
LERMGANSLE
560
RMGPAMGPAL
570
GAGIERMGLA
580
MGGAGGASFD
590
RTIEMERGNF
600
GGSFAGSFGG
610
AGGHAPGVAR
620
KACQIFVRNL
630
PFDFTWKMLK
640
DKFNECGHVL
650
YADIKMENGK
660
SKGCGVVKFE
670
SPEVAERACR
680
MMNGMKLSGR
690
EIDVRIDRNA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0016363 | nuclear matrix |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0042382 | paraspeckles |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0048306 | calcium-dependent protein binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:1990405 | protein antigen binding |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000380 | alternative mRNA splicing, via spliceosome |
| Biological Process | GO:1990831 | cellular response to carcinoembryonic antigen |
| Biological Process | GO:0071222 | cellular response to lipopolysaccharide |
| Biological Process | GO:1904591 | positive regulation of protein import |
| Biological Process | GO:1900182 | positive regulation of protein localization to nucleus |
| Biological Process | GO:0099175 | regulation of postsynapse organization |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.