Search Results
Overview
| Uniprot ID | Q62908 |
|---|---|
| Protein Name | Cysteine and glycine-rich protein 2 |
| Gene Name | Csrp2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 112 | NTSKFAQKYGGAEKC |
Function
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system
Protein Sequence
10
MPVWGGGNKC
20
GACGRTVYHA
30
EEVQCDGRTF
40
HRCCFLCMVC
50
RKNLDSTTVA
60
IHDEEIYCKS
70
CYGKKYGPKG
80
YGYGQGAGTL
90
NMDRGERLGI
100
KPESAQPHRP
110
TTNPNTSKFA
120
QKYGGAEKCS
130
RCGDSVYAAE
140
KIIGAGKPWH
150
KNCFRCAKCG
160
KSLESTTLTE
170
KEGEIYCKGC
180
YAKNFGPKGF
190
GYGQGAGALV
HAQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0030018 | Z disc |
| Molecular Function | GO:0042805 | actinin binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Biological Process | GO:0060537 | muscle tissue development |
| Biological Process | GO:0045445 | myoblast differentiation |
| Biological Process | GO:0045214 | sarcomere organization |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.