Search Results
Overview
| Uniprot ID | Q68D86 |
|---|---|
| Protein Name | Coiled-coil domain-containing protein 102B |
| Gene Name | CCDC102B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 419 | SQIDLQEKNQELLNL |
Function
During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion (PubMed:30404835). During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation (PubMed:30404835). Contributes to CROCC/rootletin filament formation (PubMed:30404835)
Protein Sequence
10
MNLDSIHRLI
20
EETQIFQMQQ
30
SSIKSRGDMV
40
APASPPRDTC
50
NTCFPLHGLQ
60
SHAAHNFCAH
70
SYNTNKWDIC
80
EELRLRELEE
90
VKARAAQMEK
100
TMRWWSDCTA
110
NWREKWSKVR
120
AERNSAREEG
130
RQLRIKLEMA
140
MKELSTLKKK
150
QSLPPQKEAL
160
EAKVTQDLKL
170
PGFVEESCEH
180
TDQFQLSSQM
190
HESIREYLVK
200
RQFSTKEDTN
210
NKEQGVVIDS
220
LKLSEEMKPN
230
LDGVDLFNNG
240
GSGNGETKTG
250
LRLKAINLPL
260
ENEVTEISAL
270
QVHLDEFQKI
280
LWKEREMRTA
290
LEKEIERLES
300
ALSLWKWKYE
310
ELKESKPKNV
320
KEFDILLGQH
330
NDEMQELSGN
340
IKEESKSQNS
350
KDRVICELRA
360
ELERLQAENT
370
SEWDKREILE
380
REKQGLEREN
390
RRLKIQVKEM
400
EELLDKKNRL
410
SANSQSPDFK
420
MSQIDLQEKN
430
QELLNLQHAY
440
YKLNRQYQAN
450
IAELTHANNR
460
VDQNEAEVKK
470
LRLRVEELKQ
480
GLNQKEDELD
490
DSLNQIRKLQ
500
RSLDEEKERN
510
ENLETELRHL
QNW
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005814 | centriole |
| Molecular Function | GO:0120283 | protein serine/threonine kinase binding |
| Biological Process | GO:0010457 | centriole-centriole cohesion |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.