Search Results
Overview
| Uniprot ID | Q68DH5 |
|---|---|
| Protein Name | G protein-coupled receptor-associated protein LMBRD2 |
| Gene Name | LMBRD2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 28 | LHRYGDFKKQHRLVI |
| 29 | HRYGDFKKQHRLVII |
Function
Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway (PubMed:28388415). May also regulate other G protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable)
Protein Sequence
10
MSGAALGLEI
20
VFVFFLALFL
30
LHRYGDFKKQ
40
HRLVIIGTLL
50
AWYLCFLIVF
60
ILPLDVSTTI
70
YNRCKHAAAN
80
SSPPENSNIT
90
GLYATANPVP
100
SQHPCFKPWS
110
YIPDGIMPIF
120
WRVVYWTSQF
130
LTWILLPFMQ
140
SYARSGGFSI
150
TGKIKTALIE
160
NAIYYGTYLL
170
IFGAFLIYVA
180
VNPHLHLEWN
190
QLQTIGIAAA
200
NTWGLFLLVL
210
LLGYGLVEIP
220
RSYWNGAKRG
230
YLLMKTYFKA
240
AKLMTEKADA
250
EENLEDAMEE
260
VRKVNESIKY
270
NHPLRKCVDT
280
ILKKCPTEYQ
290
EKMGRNMDDY
300
EDFDEKHSIY
310
PSEKSLVKLH
320
KQVIYSVQRH
330
RRTQVQWQIL
340
LEQAFYLEDV
350
AKNETSATHQ
360
FVHTFQSPEP
370
ENRFIQYFYN
380
PTFEWYWECL
390
LRPWFYKILA
400
VVLSIFSVIV
410
VWSECTFFST
420
TPVLSLFAVF
430
IQLAEKTYNY
440
IYIEIACFLS
450
IFFLSICVYS
460
TVFRIRVFNY
470
YYLASHHQTD
480
AYSLLFSGML
490
FCRLTPPLCL
500
NFLGLTHMDS
510
SISHKNTQPT
520
AYTSIMGSMK
530
VLSFIADGFY
540
IYYPMLVVIL
550
CIATYFSLGT
560
RCLNLLGFQQ
570
FMGDDDMTSD
580
LVNEGKELIR
590
KEKRKRQRQE
600
EGENRRREWK
610
ERYGHNREDS
620
TRNRNIHTDP
630
KESNFSDVNT
640
NRSAFKYTRA
650
NNRTERDRIE
660
LLQDAEPLDF
670
NAETFTDDPL
680
ESESGRYQPG
690
GRYLSMSRSD
IFNDV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0071875 | adrenergic receptor signaling pathway |
Reference
PMID: N/A