Search Results
Overview
| Uniprot ID | Q6DN03 |
|---|---|
| Protein Name | Putative histone H2B type 2-C |
| Gene Name | H2BC20P |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 21 | GSKKAVTKAQKKDGK |
| 86 | SRLAHYNKRSTITSR |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MPEPAKFAPA
20
PKKGSKKAVT
30
KAQKKDGKKR
40
KRSRKESYSI
50
YVYKVLKRVH
60
PDTGIWCKAM
70
GIMNSFLNDI
80
FERIAGEASR
90
LAHYNKRSTI
100
TSRRSRRPCA
110
CCCPASWPST
120
PCPRAPRRSP
130
STPAPSESLP
140
GPGARSLPPS
150
LPPRVAGCFV
160
SKGSFQGHLT
170
TSVKESFLCC
180
QSQLMFLASR
190
LVNFRRAHNT
KHR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0019731 | antibacterial humoral response |
| Biological Process | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide |
| Biological Process | GO:0006325 | chromatin organization |
| Biological Process | GO:0002227 | innate immune response in mucosa |
Reference
PMID: N/A