Search Results
Overview
| Uniprot ID | Q6FGX9 |
|---|---|
| Protein Name | Adenylate kinase isoenzyme 1 |
| Gene Name | AK1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 27 | GKGTQCEKIVQKYGY |
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP
Protein Sequence
10
MEEKLKKTKI
20
IFVVGGPGSG
30
KGTQCEKIVQ
40
KYGYTHLSTG
50
DLLRSEVSSG
60
SARGKKLSEI
70
MEKGQLVPLE
80
TVLDMLRDAM
90
VAKVNTSKGF
100
LIDGYPREVQ
110
QGEEFERRIG
120
QPTLLLYVDA
130
GPETMTQRLL
140
KRGETSGRVD
150
DNEETIKKRL
160
ETYYKATEPV
170
IAFYEKRGIV
180
RKVNAEGSVD
190
SVFSQVCTHL
DALK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0001520 | outer dense fiber |
| Molecular Function | GO:0004017 | AMP kinase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0004550 | nucleoside diphosphate kinase activity |
| Biological Process | GO:0006172 | ADP biosynthetic process |
| Biological Process | GO:0046033 | AMP metabolic process |
| Biological Process | GO:0046034 | ATP metabolic process |
| Biological Process | GO:0015949 | nucleobase-containing small molecule interconversion |
| Biological Process | GO:0009142 | nucleoside triphosphate biosynthetic process |
Reference
PMID: N/A