Search Results
Overview
| Uniprot ID | Q6FHC3 |
|---|---|
| Protein Name | Calponin |
| Gene Name | CNN2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 239 | DTKLGTDKCDNSSMS |
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Protein Sequence
10
MSSTQFNKGP
20
SYGLSAEVKN
30
RLLSKYDPQK
40
EAELRTWIEG
50
LTGLSIGPDF
60
QKGLKDGTIL
70
CTLMNKLQLG
80
SVPKINRSMQ
90
NWHQLENLSN
100
FIKAMVSYGM
110
NPVDLFEAND
120
LFESGNMTQV
130
QVSLLALAGK
140
AKTKGLQSGV
150
DIGVKYSEKQ
160
ERNFDDATMK
170
AGQCVIGLQM
180
GTNKCASQSG
190
MTAYGTRRHL
200
YDPKNHILPP
210
MDHSTISLQM
220
GTNKCSSQVG
230
MTAPGTRRHI
240
YDTKLGTDKC
250
DNSSMSLQMG
260
YTQGANQSGQ
270
VFGLGRQIYD
280
PKYCPQGTVA
290
DGAPSGTGDC
300
PDPGEVPEYP
PYYQEEAGY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0031032 | actomyosin structure organization |
Reference
PMID: N/A