Search Results
Overview
| Uniprot ID | Q6IAV5 |
|---|---|
| Protein Name | Succinyl-CoA:3-ketoacid-coenzyme A transferase |
| Gene Name | OXCT |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 26 | GSGATWYKGCVCSFS |
Function
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate
Protein Sequence
10
MAALKLLSSG
20
LRLCASARGS
30
GATWYKGCVC
40
SFSTSAHRHT
50
KFYTDPVEAV
60
KDIPDGATVL
70
VGGFGLCGIP
80
ENLIDALLKT
90
GVKGLTAVSN
100
NAGVDNFGLG
110
LLLRSKQIKR
120
MVSSYVGENA
130
EFERQYLSGE
140
LEVELTPQGT
150
LAERIRAGGA
160
GVPAFYTPTG
170
YGTLVQEGGS
180
PIKYNKDGSV
190
AIASKPREVR
200
EFNGQHFILE
210
EAITGDFALV
220
KAWKADRAGN
230
VIFRKSARNF
240
NLPMCKAAET
250
TVVEVEEIVD
260
IGAFAPEDIH
270
IPQIYVHRLI
280
KGEKYEKRIE
290
RLSIRKEGDG
300
EAKSAKPGDD
310
VRERIIKRAA
320
LEFEDGMYAN
330
LGIGIPLLAS
340
NFISPNITVH
350
LQSENGVLGL
360
GPYPRQHEAD
370
ADFINAGKET
380
VTILPGASFF
390
SSDESFAMIR
400
GGHVDLTMLG
410
AMQVSKYGDL
420
ANWMIPGKMV
430
KGMGGAMDLV
440
SSAKTKVVVT
450
MEHSAKGNAH
460
KIMEKCTLPL
470
TGKQCVNRII
480
TEKAVFDVDK
490
KKGLTLIELW
500
EGLTVDDVQK
510
STGCDFAVSP
520
KLMPMQQIAN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0008260 | succinyl-CoA:3-oxo-acid CoA-transferase activity |
| Biological Process | GO:0046952 | ketone body catabolic process |
Reference
PMID: N/A