Search Results
Overview
| Uniprot ID | Q6K9N6 |
|---|---|
| Protein Name | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial |
| Gene Name | Os02g0621700 |
| Organism | Oryza sativa subsp. japonica |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | QGGVHIVKAEEAESL |
| 188 | KVPIDVFKGITDDDA |
| 377 | AAKQVDLKVPVVVRL |
| 63 | EEVKNTLKNVFPSEK |
| 70 | KNVFPSEKEIVVKSQ |
Function
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
Protein Sequence
10
MVRGSLGKLA
20
SRALSVAGKW
30
QHQQLRRLNI
40
HEYQGAELMG
50
KYGINVPRGA
60
AAGSVEEVKN
70
TLKNVFPSEK
80
EIVVKSQILA
90
GGRGLGTFKS
100
GLQGGVHIVK
110
AEEAESLAAK
120
MLGQILVTKQ
130
TGPQGKIVSK
140
VYLCEKLSLV
150
NEMYFAITLD
160
RNTAGPLIIA
170
CSKGGTSIED
180
LAEKYPDMII
190
KVPIDVFKGI
200
TDDDAAKVVD
210
GLAPKTADRQ
220
SSIEQIKKLY
230
ELFCKSDCTL
240
LEINPLAETA
250
DNKLVAADAK
260
LNFDDNAAFR
270
QKEIFAMRDT
280
TQEDPREVAA
290
AKADLNYIGL
300
DGEIGCMVNG
310
AGLAMATMDI
320
IKLHGGTPAN
330
FLDVGGSASE
340
GQVVEAFKIL
350
TSDDRVKAIL
360
VNIFGGIMKC
370
DVIASGIVNA
380
AKQVDLKVPV
390
VVRLEGTNVD
400
QGKRILKESG
410
MTLITAEDLD
420
DAAEKAVKAS
VK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0042709 | succinate-CoA ligase complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004775 | succinate-CoA ligase (ADP-forming) activity |
| Biological Process | GO:0006104 | succinyl-CoA metabolic process |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] Meng X, Baine JM, Yan T, Wang S. Comprehensive Analysis of Lysine Lactylation in Rice (Oryza sativa) Grains.. J Agric Food Chem 69(29):8287-8297. 2021 Jul 28. PMID: 34264677.