Search Results

Overview

Uniprot IDQ6NUQ4
Protein NameTransmembrane protein 214
Gene NameTMEM214
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
69 RGFENIMKRQNKEQV
94 GNKKQPKKVATPPNQ

Function

Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress

Protein Sequence

10 MATKTAGVGR 20 WEVVKKGRRP 30 GVGAGAGGRG 40 GGRNRRALGE 50 ANGVWKYDLT 60 PAIQTTSTLY 70 ERGFENIMKR 80 QNKEQVPPPA 90 VEPKKPGNKK 100 QPKKVATPPN 110 QNQKQGRFRS 120 LEEALKALDV 130 ADLQKELDKS 140 QSVFSGNPSI 150 WLKDLASYLN 160 YKLQAPLSEP 170 TLSQHTHDYP 180 YSLVSRELRG 190 IIRGLLAKAA 200 GSLELFFDHC 210 LFTMLQELDK 220 TPGESLHGYR 230 ICIQAILQDK 240 PKIATANLGK 250 FLELLRSHQS 260 RPAKCLTIMW 270 ALGQAGFANL 280 TEGLKVWLGI 290 MLPVLGIKSL 300 SPFAITYLDR 310 LLLMHPNLTK 320 GFGMIGPKDF 330 FPLLDFAYMP 340 NNSLTPSLQE 350 QLCQLYPRLK 360 VLAFGAKPDS 370 TLHTYFPSFL 380 SRATPSCPPE 390 MKKELLSSLT 400 ECLTVDPLSA 410 SVWRQLYPKH 420 LSQSSLLLEH 430 LLSSWEQIPK 440 KVQKSLQETI 450 QSLKLTNQEL 460 LRKGSSNNQD 470 VVTCDMACKG 480 LLQQVQGPRL 490 PWTRLLLLLL 500 VFAVGFLCHD 510 LRSHSSFQAS 520 LTGRLLRSSG 530 FLPASQQACA 540 KLYSYSLQGY 550 SWLGETLPLW 560 GSHLLTVVRP 570 SLQLAWAHTN 580 ATVSFLSAHC 590 ASHLAWFGDS 600 LTSLSQRLQI 610 QLPDSVNQLL 620 RYLRELPLLF 630 HQNVLLPLWH 640 LLLEALAWAQ 650 EHCHEACRGE 660 VTWDCMKTQL 670 SEAVHWTWLC 680 LQDITVAFLD WALALISQQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005881 cytoplasmic microtubule
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0005794 Golgi apparatus
Biological Process GO:0006915 apoptotic process

Reference

PMID: N/A