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Overview

Uniprot IDQ6NXT1
Protein NameAnkyrin repeat domain-containing protein 54
Gene NameANKRD54
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
85 PRDELRCKIPAGRLR

Function

Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation

Protein Sequence

10 MAAAAGDADD 20 EPRSGHSSSE 30 GECAVAPEPL 40 TDAEGLFSFA 50 DFGSALGGGG 60 AGLSGRASGG 70 AQSPLRYLHV 80 LWQQDAEPRD 90 ELRCKIPAGR 100 LRRAARPHRR 110 LGPTGKEVHA 120 LKRLRDSANA 130 NDVETVQQLL 140 EDGADPCAAD 150 DKGRTALHFA 160 SCNGNDQIVQ 170 LLLDHGADPN 180 QRDGLGNTPL 190 HLAACTNHVP 200 VITTLLRGGA 210 RVDALDRAGR 220 TPLHLAKSKL 230 NILQEGHAQC 240 LEAVRLEVKQ 250 IIHMLREYLE 260 RLGQHEQRER 270 LDDLCTRLQM 280 TSTKEQVDEV 290 TDLLASFTSL 300 SLQMQSMEKR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0030496 midbody
Cellular Component GO:0005634 nucleus
Molecular Function GO:0019887 protein kinase regulator activity
Molecular Function GO:0044877 protein-containing complex binding
Biological Process GO:0045648 positive regulation of erythrocyte differentiation
Biological Process GO:1902531 regulation of intracellular signal transduction

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.