Search Results
Overview
| Uniprot ID | Q6PGH2 |
|---|---|
| Protein Name | Jupiter microtubule associated homolog 2 |
| Gene Name | Jpt2 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 67 | RTNPPGGKGSGIFDE |
Function
Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein required for NAADP-evoked intracellular calcium release. Confers NAADP-sensitivity to the two pore channels (TPCs) complex. Enables NAADP to activate Ca(2+) release from the endoplasmic reticulum through ryanodine receptors
Protein Sequence
10
MFQGADSQAG
20
KSGSRSMKPP
30
GGESSDLFGS
40
PEEGISSSKP
50
NRMASNIFGP
60
TEEPKNIPKR
70
TNPPGGKGSG
80
IFDESTPVQT
90
RQRLNPPGGK
100
TSDIFGSPVT
110
ATAPLAHPNK
120
PKDHVLLCEG
130
EDSKSDLKAA
140
TDSTPRGEQS
150
DKGSSKEVEH
160
AKIPEPTPTV
170
DSHEPRLGPR
180
PRSHNKVLNP
190
PGGKSSLSFY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0075509 | endocytosis involved in viral entry into host cell |
| Biological Process | GO:0050848 | regulation of calcium-mediated signaling |
Reference
[1] Sung E, Sim H, Cho YC, Lee W, Bae JS et al.. Global Profiling of Lysine Acetylation and Lactylation in Kupffer Cells.. J Proteome Res 22(12):3683-3691. 2023 Dec 1. PMID: 37897433.