Search Results
Overview
| Uniprot ID | Q6PI98 |
|---|---|
| Protein Name | INO80 complex subunit C |
| Gene Name | INO80C |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | HGGAVAGKKNRTWKN |
| 101 | GGAVAGKKNRTWKNL |
Function
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair
Protein Sequence
10
MAAQIPIVAT
20
TSTPGIVRNS
30
KKRPASPSHN
40
GSSGGGYGAS
50
KKKKASASSF
60
AQGISMEAMS
70
ENKMVPSEFS
80
TGPVEKAAKP
90
LPFKDPNFVH
100
SGHGGAVAGK
110
KNRTWKNLKQ
120
ILASERALPW
130
QLNDPNYFSI
140
DAPPSFKPAK
150
KYSDVSGLLA
160
NYTDPQSKLR
170
FSTIEEFSYI
180
RRLPSDVVTG
190
YLALRKATSI
VP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0031011 | Ino80 complex |
| Cellular Component | GO:0071339 | MLL1 complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Biological Process | GO:0006338 | chromatin remodeling |
| Biological Process | GO:0006310 | DNA recombination |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045739 | positive regulation of DNA repair |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:1904507 | positive regulation of telomere maintenance in response to DNA damage |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0033044 | regulation of chromosome organization |
| Biological Process | GO:0006275 | regulation of DNA replication |
| Biological Process | GO:0060382 | regulation of DNA strand elongation |
| Biological Process | GO:0045995 | regulation of embryonic development |
| Biological Process | GO:0000723 | telomere maintenance |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.