Search Results

Overview

Uniprot IDQ6PJG2
Protein NameMitotic deacetylase-associated SANT domain protein
Gene NameMIDEAS
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
1004 AGGQASEKPREGTGK
1022 ALPFSEKKKKTETFS
1030 KKTETFSKTQNQENT
1041 QENTFPCKKCGR***
1042 ENTFPCKKCGR****
166 YNHPEALKREKAGGP
169 PEALKREKAGGPQLD
493 SGSEEKRKSVLASTT
501 SVLASTTKCGVEFSE
514 SEPSLATKRAREDSG
912 VDIKTSQKFPRVPLP

Function

No function data available.

Protein Sequence

10 MNLQAQPKAQ 20 NKRKRCLFGG 30 QEPAPKEQPP 40 PLQPPQQSIR 50 VKEEQYLGHE 60 GPGGAVSTSQ 70 PVELPPPSSL 80 ALLNSVVYGP 90 ERTSAAMLSQ 100 QVASVKWPNS 110 VMAPGRGPER 120 GGGGGVSDSS 130 WQQQPGQPPP 140 HSTWNCHSLS 150 LYSATKGSPH 160 PGVGVPTYYN 170 HPEALKREKA 180 GGPQLDRYVR 190 PMMPQKVQLE 200 VGRPQAPLNS 210 FHAAKKPPNQ 220 SLPLQPFQLA 230 FGHQVNRQVF 240 RQGPPPPNPV 250 AAFPPQKQQQ 260 QQQPQQQQQQ 270 QQAALPQMPL 280 FENFYSMPQQ 290 PSQQPQDFGL 300 QPAGPLGQSH 310 LAHHSMAPYP 320 FPPNPDMNPE 330 LRKALLQDSA 340 PQPALPQVQI 350 PFPRRSRRLS 360 KEGILPPSAL 370 DGAGTQPGQE 380 ATGNLFLHHW 390 PLQQPPPGSL 400 GQPHPEALGF 410 PLELRESQLL 420 PDGERLAPNG 430 REREAPAMGS 440 EEGMRAVSTG 450 DCGQVLRGGV 460 IQSTRRRRRA 470 SQEANLLTLA 480 QKAVELASLQ 490 NAKDGSGSEE 500 KRKSVLASTT 510 KCGVEFSEPS 520 LATKRAREDS 530 GMVPLIIPVS 540 VPVRTVDPTE 550 AAQAGGLDED 560 GKGPEQNPAE 570 HKPSVIVTRR 580 RSTRIPGTDA 590 QAQAEDMNVK 600 LEGEPSVRKP 610 KQRPRPEPLI 620 IPTKAGTFIA 630 PPVYSNITPY 640 QSHLRSPVRL 650 ADHPSERSFE 660 LPPYTPPPIL 670 SPVREGSGLY 680 FNAIISTSTI 690 PAPPPITPKS 700 AHRTLLRTNS 710 AEVTPPVLSV 720 MGEATPVSIE 730 PRINVGSRFQ 740 AEIPLMRDRA 750 LAAADPHKAD 760 LVWQPWEDLE 770 SSREKQRQVE 780 DLLTAACSSI 790 FPGAGTNQEL 800 ALHCLHESRG 810 DILETLNKLL 820 LKKPLRPHNH 830 PLATYHYTGS 840 DQWKMAERKL 850 FNKGIAIYKK 860 DFFLVQKLIQ 870 TKTVAQCVEF 880 YYTYKKQVKI 890 GRNGTLTFGD 900 VDTSDEKSAQ 910 EEVEVDIKTS 920 QKFPRVPLPR 930 RESPSEERLE 940 PKREVKEPRK 950 EGEEEVPEIQ 960 EKEEQEEGRE 970 RSRRAAAVKA 980 TQTLQANESA 990 SDILILRSHE 1000 SNAPGSAGGQ 1010 ASEKPREGTG 1020 KSRRALPFSE 1030 KKKKTETFSK 1040 TQNQENTFPC KKCGR

Gene Ontology

Classification GO ID Description
Biological Process GO:0045995 regulation of embryonic development
Cellular Component GO:0000118 histone deacetylase complex
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005667 transcription regulator complex
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0003714 transcription corepressor activity
Biological Process GO:0006325 chromatin organization
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0006357 regulation of transcription by RNA polymerase II

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.