Search Results
Overview
| Uniprot ID | Q6URK8 |
|---|---|
| Protein Name | Sperm microtubule inner protein 8 |
| Gene Name | SPMIP8 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 189 | SLDRYGQKPLPFDSL |
Function
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in flagellum axoneme. May serve to reinforce and thus stabilize the microtubule structure in the sperm flagella
Protein Sequence
10
MARIIDLVPW
20
DDGSTHVYAS
30
PAILLPMERQ
40
RNQLAGVKQQ
50
LYHPALPTLR
60
HMDRDTVKAC
70
LPDEHCQSTT
80
YCRKDEFDNA
90
HFTLLGVPNK
100
PLQCLDITAT
110
GQKLRNRYHE
120
GKLAPIAPGI
130
NRVDWPCFTR
140
AIEDWSHFVS
150
SAGEFKLPCL
160
RKRAEGLSGY
170
AVRYLKPDVT
180
QTWRYCLSQN
190
PSLDRYGQKP
200
LPFDSLNTFR
210
SFGSSYSRVN
YLTPWH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0160111 | axonemal A tubule inner sheath |
| Cellular Component | GO:0036126 | sperm flagellum |
| Biological Process | GO:0030317 | flagellated sperm motility |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.