Search Results

Overview

Uniprot IDQ6UW68
Protein NameTransmembrane protein 205
Gene NameTMEM205
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
122 WALQTVEKERGLGGE
149 QLREKDPKYSALRQN

Function

In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin

Protein Sequence

10 MEEGGNLGGL 20 IKMVHLLVLS 30 GAWGMQMWVT 40 FVSGFLLFRS 50 LPRHTFGLVQ 60 SKLFPFYFHI 70 SMGCAFINLC 80 ILASQHAWAQ 90 LTFWEASQLY 100 LLFLSLTLAT 110 VNARWLEPRT 120 TAAMWALQTV 130 EKERGLGGEV 140 PGSHQGPDPY 150 RQLREKDPKY 160 SALRQNFFRY 170 HGLSSLCNLG 180 CVLSNGLCLA GLALEIRSL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016020 membrane

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.