Search Results
Overview
| Uniprot ID | Q6UWM9 |
|---|---|
| Protein Name | UDP-glucuronosyltransferase 2A3 |
| Gene Name | UGT2A3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 281 | FVGGLHCKPAKALPK |
Function
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions by conjugating glucuronic acid to lipophilic substrates, thereby increasing their water solubility and facilitating excretion. Catalyzes the glucuronidation of the bile acids hyodeoxycholic acid, deoxycholic acid, chenodeoxycholic acid, and ursodeoxycholic acid
Protein Sequence
10
MRSDKSALVF
20
LLLQLFCVGC
30
GFCGKVLVWP
40
CDMSHWLNVK
50
VILEELIVRG
60
HEVTVLTHSK
70
PSLIDYRKPS
80
ALKFEVVHMP
90
QDRTEENEIF
100
VDLALNVLPG
110
LSTWQSVIKL
120
NDFFVEIRGT
130
LKMMCESFIY
140
NQTLMKKLQE
150
TNYDVMLIDP
160
VIPCGDLMAE
170
LLAVPFVLTL
180
RISVGGNMER
190
SCGKLPAPLS
200
YVPVPMTGLT
210
DRMTFLERVK
220
NSMLSVLFHF
230
WIQDYDYHFW
240
EEFYSKALGR
250
PTTLCETVGK
260
AEIWLIRTYW
270
DFEFPQPYQP
280
NFEFVGGLHC
290
KPAKALPKEM
300
ENFVQSSGED
310
GIVVFSLGSL
320
FQNVTEEKAN
330
IIASALAQIP
340
QKVLWRYKGK
350
KPSTLGANTR
360
LYDWIPQNDL
370
LGHPKTKAFI
380
THGGMNGIYE
390
AIYHGVPMVG
400
VPIFGDQLDN
410
IAHMKAKGAA
420
VEINFKTMTS
430
EDLLRALRTV
440
ITDSSYKENA
450
MRLSRIHHDQ
460
PVKPLDRAVF
470
WIEFVMRHKG
480
AKHLRSAAHD
490
LTWFQHYSID
500
VIGFLLACVA
510
TAIFLFTKCF
520
LFSCQKFNKT
RKIEKRE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0015020 | glucuronosyltransferase activity |
| Biological Process | GO:0006805 | xenobiotic metabolic process |
Reference
PMID: N/A