Search Results

Overview

Uniprot IDQ6XE24
Protein NameRNA-binding motif, single-stranded-interacting protein 3
Gene NameRBMS3
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
161 QELENMLKPFGHVIS

Function

Binds poly(A) and poly(U) oligoribonucleotides

Protein Sequence

10 MGKRLDQPQM 20 YPQYTYYYPH 30 YLQTKQSYAP 40 APHPMAPPSP 50 STNSSSNNSS 60 NNSSGEQLSK 70 TNLYIRGLPP 80 GTTDQDLIKL 90 CQPYGKIVST 100 KAILDKNTNQ 110 CKGYGFVDFD 120 SPAAAQKAVA 130 SLKANGVQAQ 140 MAKQQEQDPT 150 NLYISNLPIS 160 MDEQELENML 170 KPFGHVISTR 180 ILRDANGVSR 190 GVGFARMEST 200 EKCEVVIQHF 210 NGKYLKTPPG 220 IPAPSEPLLC 230 KFADGGQKKR 240 QNQSKYTQNG 250 RPWPREGEAG 260 MALTYDPTAA 270 IQNGFYSSPY 280 SIATNRMIPQ 290 TSITPFIAAS 300 PVSTYQVQST 310 SWMPHPPYVM 320 QPTGAVITPT 330 MDHPMSMQPA 340 NMMGPLTQQM 350 NHLSLGTTGT 360 IQSQDRIMIL 370 HQLLCQYMTA 380 AAPMQGTYIP 390 QYTPVPPTAV 400 SIEGVVADTS 410 PQTVAPSSQD 420 TSGQQQQIAV 430 DTSNEHAPAY SYQQSKP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005634 nucleus
Cellular Component GO:1990904 ribonucleoprotein complex
Molecular Function GO:0035925 mRNA 3'-UTR AU-rich region binding
Molecular Function GO:0003730 mRNA 3'-UTR binding
Molecular Function GO:0008143 poly(A) binding
Molecular Function GO:0008266 poly(U) RNA binding
Biological Process GO:0002357 defense response to tumor cell
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0010628 positive regulation of gene expression

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.